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  • Mipletamig plus venetoclax and azacitidine showed 93% clinical benefit in frontline TP53-mutated AMLSep 3, 2026

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  • Aptevo advances its next-generation trispecific candidate toward clinical developmentSep 24, 2026
  • Aptevo files patent to strengthen its dual-targeting solid tumor immunotherapy strategyJul 27, 2026
  • Aptevo reported strong clinical outcomes with high benefit and remission rates in frontline AML patients, outperforming benchmarksMay 6, 2026
  • Mipletamig showed an 86% clinical benefit rate with no CRS as evaluable AML patient data increased significantlyMar 10, 2026
  • Aptevo debuts first trispecific antibody candidate, APVO451, with preclinical data demonstrating immune activation in hard-to-treat solid tumorsNov 10, 2025

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