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Ionis Pharmaceuticals

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Daily updates

  • Ionis received FDA approval for Zanvastro as the first disease-modifying Alexander disease therapySep 7, 2026

FDA designations

  • Ionis Receives FDA Breakthrough Therapy Designation for ION582 in Angelman SyndromeSep 9, 2025

News

  • CHMP recommends TRYNGOLZA (olezarsen) for EU approval to treat severe hypertriglyceridemiaOct 16, 2026
  • Ionis reports positive interim results from partner Roche's Phase 3 IMAgINATION study in IgA nephropathySep 23, 2026
  • Ionis reports positive topline Phase 3 FUSION results for ulefnersen, advancing a potential first disease-modifying treatment for FUS-ALSSep 22, 2026
  • Ionis received FDA approval for Zanvastro in Alexander disease, making it the first disease-modifying therapy for the rare disorderSep 7, 2026
  • Ionis and partner Biogen presented Phase 2 CELIA data showing meaningful clinical benefits and strong tau reduction with Diranersen in early Alzheimer's diseaseJul 15, 2026

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